Graduate studies in the Department of Biochemistry can lead to an M.P.S., M.S.
or Ph.D. degree. Students may choose from research areas in plant molecular biology,
physical biochemistry, biophysics, and cell regulatory systems. Financial aid
is available on a competitive basis, primarily in the form of graduate teaching
assistantships. Research assistantships and University fellowships are also available.
All of the faculty are actively involved in research that is supported at the
federal level. Students admitted to the graduate program in Biochemistry may also
carry out their research with faculty listed under Microbiology in this catalog,
in a number of laboratories in other departments at the University, the Jackson
Laboratory in Bar Harbor, the Maine Medical Center Research Institute in Portland,
or through cooperative institutional arrangements and Associate faculty or staff.
The Ph.D. degree in Biochemistry and Molecular Biology is awarded for significant
and original contributions to basic knowledge through research. A Ph.D. degree
in Functional Genomics may also be obtained through the Interdisciplinary Ph.D.
program. The curriculum plan is variable and will take into account each student’s
goals for graduate study and the content and quality of his or her undergraduate
The Master’s program prepares students for further studies toward the Ph.D.,
or medical degrees, as well as for careers in academic or industrial research,
or teaching. The M.P.S., Master of Professional Studies, is a non-thesis Master’s
Prerequisite for admission to these programs is the completion of undergraduate
work in chemistry, mathematics, and physics substantially equivalent to that required
of undergraduate students at this institution whose major is Biochemistry.
John T. Singer, Ph.D. (Georgia, 1983), Professor and Chair. Molecular genetics and microbial
Katherine J. Boettcher, Ph.D. (University of Southern California, 1994), Assistant Professor. Bacterial
physiology and adaptation, invertebrate microbiology, marine microbiology.
Robert E. Cashon, Ph.D. (Johns Hopkins University, 1981), Assistant Professor. Protein structure-function
Dorothy E. Croall, Ph.D. (University of Rochester Medical School, 1979) Professor. Structure and
regulation of Ca-dependent proteolytic systems in mammalian cells.
Daniel L. Distel, Ph.D. (Scripps Institute of Oceanography, UCSD, 1988), Associate Professor.
Symbiotic relationships between bacteria and marine organisms.
Robert E. Gundersen, Ph.D. (University of Texas-Austin, 1983), Associate Professor. The Role of
signal transduction during growth and development in eukaryotes.
Keith W. Hutchison, Ph.D. (Wisconsin-Madison, 1974) Professor. Regulation of gene expression during
growth and maturation of conifers.
Carol H. Kim, Ph.D. (Cornell, 1992), Associate Professor. Viral pathogens and vaccine development
in a zebrafish model system.
Gary M. King, Ph.D. (Georgia 1978), Professor. Microbial ecology and biogeochemistry.
Gregory D. Mayer, Ph.D. (Kentucky, 2001), Assistant Professor. Molecular/Environmental Toxicology:
Gene regulation by heavy metals.
Charles E. Moody, Ph.D. (Rhode Island, 1976), Associate Professor and Graduate Coordinator. Developmental
and comparative immunology.
Bruce L. Nicholson, Ph.D. (Maryland, 1969), Professor of Microbiology. Animal viruses, particularly
viruses of fish and other poikilothermic vertebrates.
Mary E. Rumpho, Ph.D. (Washington State, 1982), Professor. Mollusk and algal chloroplast symbiosis,
physiological genomics of low oxygen stress in plants, anticancer metabolites
from plants and mollusks.
Rebecca J. Van Beneden, Ph.D. (The Johns Hopkins University, 1983), Professor. Molecular oncology and
aquatic toxicology; the role of cellular oncogenes and tumor suppressor genes
in response to environmental toxicants; regulation of gene expression; molecular
mechanisms of tumorigenesis in non-mammalian models.
Associate Faculty Jackson Laboratory
Judith A. Blake, Ph.D. (Harvard, 1981). Bioinformatics; the development and structuring of bio-ontologies
for molecular information.
Gragory A. Cox, Ph.D. (University of Michigan, 1994).
Tatyana V. Golovkina, Ph.D. (USSR Academy of Medical Sciences, 1989). Interaction between retroviruses and
Thomas Gridley, Ph.D. (Massachusetts Institute of Technology, 1985). Mouse developmental genetics
and models for human disease.
Shaoguang Li, Ph.D., M.D. Tulane, 1996. Molecular basis of leukemias.
Timothy P. O’Brien, Ph.D. (University of Illinois, 1992). The role of signaling networks in mouse
development and genomic regulatory network analysis.
Luanne L. Peters, Ph.D. (University of Maine, 1984).
Derry C. Roopenian, Ph.D. (Univeristy of Minnesota, 1984). Autoimmunity, molecular phenotyping,
David V. Serreze, Ph.D. (University of Maine, 1990). Mouse models of insulin-dependent diabetes;
the genetic basis for immune tolerance to endogenous proteins.
Lindsay S. Shopland, Ph.D. (Cornell, 1996), Research Assistant Professor. Genome organization and
chromosome structure within the cell nucleus.
Leonard D. Shultz, Ph.D. (University of Massachusetts, Amherst, 1972). Mechanisms of immunodeficiency
John P. Sundberg, D.V.M. (Purdue University 1977), Ph.D. (University of Connecticut, 1981), Diplomate
of the American College of Veterinary Pathologists (specialist in anatomic pathology,
1982), Senior Staff Scientist (The Jackson Laboratory). Genetics and mechanisms
of skin diseases and general pathology of genetically engineered laboratory mice.
Associate Faculty Maine Medical Center Research Institute
Kenneth A. Ault, M.D. (Harvard Medical School, 1970). Platelet function as a risk factor for
cardiovascular disease, genetics and immunology.
Robert E. Friesel, Ph.D. (George Washington University, 1989). Growth factors (FGFs).
Volkhard Lindner, M.D., Ph.D. (University of Tubingen, 1991). Blood vessels and the factors that
control the growth of cells in the vessel wall.
Carla Mouta, Ph.D. (George Washington University, 1999).
Leif Oxburgh, Ph.D., D.V.M. (Swedish University, 1989. Characterization and differentiation
of nephron precursors.
Igor A. Prudovsky, Ph.D. (Russian Academy of Sciences, 1979). Molecular mechanisms of regulation
of anglogenesis and inflammation by fibroblast growth factors.
Douglas Spicer, Ph.D. (Boston University, 1992).